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Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling
AIMS: Mice deficient in IL-1 receptor 1 (hence unresponsive to both IL-1 isoforms α and β) have impaired expansive arterial remodeling due to diminished expression of matrix-degrading enzymes, especially MMP-3. Emergence of IL-1 as a target in cardiovascular disease prompted the investigation of the...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816548/ https://ncbi.nlm.nih.gov/pubmed/27032103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152474 |
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