Interleukin-1 Mediates Neuroinflammatory Changes Associated With Diet-Induced Atherosclerosis

BACKGROUND: Systemic inflammation contributes to brain pathology in cerebrovascular disease through mechanisms that are poorly understood. METHODS AND RESULTS: Here we show that atherosclerosis, a major systemic inflammatory disease, is associated with severe cerebrovascular inflammation in mice and...

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Détails bibliographiques
Auteurs principaux: Denes, Adam, Drake, Caroline, Stordy, Jing, Chamberlain, Janet, McColl, Barry W., Gram, Hermann, Crossman, David, Francis, Sheila, Allan, Stuart M., Rothwell, Nancy J.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2012
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487321/
https://ncbi.nlm.nih.gov/pubmed/23130147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.002006
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