Editorial: Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges

Por Grünewald, Thomas G. P., Fulda, Simone
Publicado no Front Oncol (2016)

Cooperation between somatic mutations and germline susceptibility variants in tumorigenesis – a dangerous liaison

Por Grünewald, Thomas G. P., Delattre, Olivier
Publicado no Mol Cell Oncol (2015)

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein

Por Orth, Martin F., Cazes, Alex, Butt, Elke, Grunewald, Thomas G. P.
Publicado no Oncotarget (2014)

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers

Por Rotblat, Barak, Grunewald, Thomas G. P., Leprivier, Gabriel, Melino, Gerry, Knight, Richard A.
Publicado em 2013

LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression

Por Vaman V. S., Anjana, Poppe, Heiko, Houben, Roland, Grunewald, Thomas G. P., Goebeler, Matthias, Butt, Elke
Publicado no PLoS One (2015)

The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

Por Sahay, Debashish, Leblanc, Raphael, Grunewald, Thomas G. P., Ambatipudi, Srikant, Ribeiro, Johnny, Clézardin, Philippe, Peyruchaud, Olivier
Publicado no Oncotarget (2015)

The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab

Por Froelich, Matthias F., Stintzing, Sebastian, Kumbrink, Jörg, Grünewald, Thomas G.P., Mansmann, Ulrich, Heinemann, Volker, Kirchner, Thomas, Jung, Andreas
Publicado no Oncotarget (2018)

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

Por Elia, Ilaria, Broekaert, Dorien, Christen, Stefan, Boon, Ruben, Radaelli, Enrico, Orth, Martin F., Verfaillie, Catherine, Grünewald, Thomas G. P., Fendt, Sarah-Maria
Publicado no Nat Commun (2017)

Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo

Por Kirschner, Andreas, Thiede, Melanie, Grünewald, Thomas G. P., Alba Rubio, Rebeca, Richter, Günther H. S., Kirchner, Thomas, Busch, Dirk H., Burdach, Stefan, Thiel, Uwe
Publicado no Oncoimmunology (2017)

Sclerosing Epithelioid Fibrosarcoma of the Bone: A Case Report of High Resistance to Chemotherapy and a Survey of the Literature

Por Grunewald, Thomas G. P., von Luettichau, Irene, Weirich, Gregor, Wawer, Angela, Behrends, Uta, Prodinger, Peter M., Jundt, Gernot, Bielack, Stefan S., Gradinger, Reiner, Burdach, Stefan
Publicado em 2010

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia

Por Frietsch, Jochen J., Kastner, Carolin, Grunewald, Thomas G. P., Schweigel, Hardy, Nollau, Peter, Ziermann, Janine, Clement, Joachim H., La Rosée, Paul, Hochhaus, Andreas, Butt, Elke
Publicado em 2014

Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8(+) T cells directed against tumor-associated antigens

Por Kirschner, Andreas, Thiede, Melanie, Blaeschke, Franziska, Richter, Günther H.S., Gerke, Julia S., Baldauf, Michaela C., Grünewald, Thomas G.P., Busch, Dirk H., Burdach, Stefan, Thiel, Uwe
Publicado no Oncotarget (2016)

Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model

Por Sannino, Giuseppina, Pasqualini, Lorenza, Ricciardelli, Eugenia, Montilla, Patricia, Soverchia, Laura, Ruggeri, Barbara, Falcinelli, Silvia, Renzi, Alessandra, Ludka, Colleen, Kirchner, Thomas, Grünewald, Thomas G. P., Ciccocioppo, Roberto, Ubaldi, Massimo, Hardiman, Gary
Publicado no Oncotarget (2016)

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

Por Somasekharan, Syam Prakash, El-Naggar, Amal, Leprivier, Gabriel, Cheng, Hongwei, Hajee, Shamil, Grunewald, Thomas G.P., Zhang, Fan, Ng, Tony, Delattre, Olivier, Evdokimova, Valentina, Wang, Yuzhuo, Gleave, Martin, Sorensen, Poul H.
Publicado no J Cell Biol (2015)

Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity

Por Schirmer, David, Grünewald, Thomas G. P., Klar, Richard, Schmidt, Oxana, Wohlleber, Dirk, Rubío, Rebeca Alba, Uckert, Wolfgang, Thiel, Uwe, Bohne, Felix, Busch, Dirk H., Krackhardt, Angela M., Burdach, Stefan, Richter, Günther H. S.
Publicado no Oncoimmunology (2016)

Human HLA-A*02:01/CHM1(+) allo-restricted T cell receptor transgenic CD8(+) T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo

Por Blaeschke, Franziska, Thiel, Uwe, Kirschner, Andreas, Thiede, Melanie, Rubio, Rebeca Alba, Schirmer, David, Kirchner, Thomas, Richter, Gunther H.S., Mall, Sabine, Klar, Richard, Riddell, Stanley, Busch, Dirk H., Krackhardt, Angela, Grunewald, Thomas G.P., Burdach, Stefan
Publicado no Oncotarget (2016)

Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metas...

Por Thiel, Uwe, Wawer, Angela, von Luettichau, Irene, Bender, Hans-Ulrich, Blaeschke, Franziska, Grunewald, Thomas G.P., Steinborn, Marc, Röper, Barbara, Bonig, Halvard, Klingebiel, Thomas, Bader, Peter, Koscielniak, Ewa, Paulussen, Michael, Dirksen, Uta, Juergens, Heribert, Kolb, Hans-Jochem, Burdach, Stefan E.G.
Publicado no Oncotarget (2016)

Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells

Por Thiel, Uwe, Schober, Sebastian J., Einspieler, Ingo, Kirschner, Andreas, Thiede, Melanie, Schirmer, David, Gall, Katja, Blaeschke, Franziska, Schmidt, Oxana, Jabar, Susanne, Ranft, Andreas, Alba Rubío, Rebeca, Dirksen, Uta, Grunewald, Thomas G. P., Sorensen, Poul H., Richter, Günther H. S., von Lüttichau, Irene Teichert, Busch, Dirk H., Burdach, Stefan E. G.
Publicado no Oncoimmunology (2017)

Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma

Por Dallmayer, Marlene, Li, Jing, Ohmura, Shunya, Alba Rubio, Rebeca, Baldauf, Michaela C., Hölting, Tilman L. B., Musa, Julian, Knott, Max M. L., Stein, Stefanie, Cidre-Aranaz, Florencia, Wehweck, Fabienne S., Romero-Pérez, Laura, Gerke, Julia S., Orth, Martin F., Marchetto, Aruna, Kirchner, Thomas, Bach, Horacio, Sannino, Giuseppina, Grünewald, Thomas G. P.
Publicado no Cell Death Dis (2019)

Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets

Por Baldauf, Michaela C., Orth, Martin F., Dallmayer, Marlene, Marchetto, Aruna, Gerke, Julia S., Rubio, Rebeca Alba, Kiran, Merve M., Musa, Julian, Knott, Maximilian M. L., Ohmura, Shunya, Li, Jing, Akpolat, Nusret, Akatli, Ayse N., Özen, Özlem, Dirksen, Uta, Hartmann, Wolfgang, de Alava, Enrique, Baumhoer, Daniel, Sannino, Giuseppina, Kirchner, Thomas, Grünewald, Thomas G. P.
Publicado no Oncotarget (2017)