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YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

Under cell stress, global protein synthesis is inhibited to preserve energy. One mechanism is to sequester and silence mRNAs in ribonucleoprotein complexes known as stress granules (SGs), which contain translationally silent mRNAs, preinitiation factors, and RNA-binding proteins. Y-box binding prote...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Somasekharan, Syam Prakash, El-Naggar, Amal, Leprivier, Gabriel, Cheng, Hongwei, Hajee, Shamil, Grunewald, Thomas G.P., Zhang, Fan, Ng, Tony, Delattre, Olivier, Evdokimova, Valentina, Wang, Yuzhuo, Gleave, Martin, Sorensen, Poul H.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384734/
https://ncbi.nlm.nih.gov/pubmed/25800057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201411047
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