Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling

Treatment‐induced adaptive pathways converge to support androgen receptor (AR) reactivation and emergence of castration‐resistant prostate cancer (PCa) after AR pathway inhibition (ARPI). We set out to explore poorly defined acute adaptive responses that orchestrate shifts in energy metabolism after...

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Bibliografski detalji
Izdano u:EMBO Mol Med
Glavni autori: Saxena, Neetu, Beraldi, Eliana, Fazli, Ladan, Somasekharan, Syam Prakash, Adomat, Hans, Zhang, Fan, Molokwu, Chidi, Gleave, Anna, Nappi, Lucia, Nguyen, Kimberly, Brar, Pavn, Nikesitch, Nicholas, Wang, Yuzhuo, Collins, Colin, Sorensen, Poul H, Gleave, Martin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103094/
https://ncbi.nlm.nih.gov/pubmed/33709547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013427
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