Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling

Treatment‐induced adaptive pathways converge to support androgen receptor (AR) reactivation and emergence of castration‐resistant prostate cancer (PCa) after AR pathway inhibition (ARPI). We set out to explore poorly defined acute adaptive responses that orchestrate shifts in energy metabolism after...

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Publicado no:EMBO Mol Med
Main Authors: Saxena, Neetu, Beraldi, Eliana, Fazli, Ladan, Somasekharan, Syam Prakash, Adomat, Hans, Zhang, Fan, Molokwu, Chidi, Gleave, Anna, Nappi, Lucia, Nguyen, Kimberly, Brar, Pavn, Nikesitch, Nicholas, Wang, Yuzhuo, Collins, Colin, Sorensen, Poul H, Gleave, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103094/
https://ncbi.nlm.nih.gov/pubmed/33709547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013427
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