Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling

Treatment‐induced adaptive pathways converge to support androgen receptor (AR) reactivation and emergence of castration‐resistant prostate cancer (PCa) after AR pathway inhibition (ARPI). We set out to explore poorly defined acute adaptive responses that orchestrate shifts in energy metabolism after...

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Détails bibliographiques
Publié dans:EMBO Mol Med
Auteurs principaux: Saxena, Neetu, Beraldi, Eliana, Fazli, Ladan, Somasekharan, Syam Prakash, Adomat, Hans, Zhang, Fan, Molokwu, Chidi, Gleave, Anna, Nappi, Lucia, Nguyen, Kimberly, Brar, Pavn, Nikesitch, Nicholas, Wang, Yuzhuo, Collins, Colin, Sorensen, Poul H, Gleave, Martin
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103094/
https://ncbi.nlm.nih.gov/pubmed/33709547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013427
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