LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is characterized by a genomic translocation generating a permanently active BCR-ABL oncogene with a complex pattern of atypically tyrosine-phosphorylated proteins that drive the malignant phenotype of CML. Recently, the LIM and SH3 domain protein 1 (LASP1) was identifi...

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Hlavní autoři: Frietsch, Jochen J., Kastner, Carolin, Grunewald, Thomas G. P., Schweigel, Hardy, Nollau, Peter, Ziermann, Janine, Clement, Joachim H., La Rosée, Paul, Hochhaus, Andreas, Butt, Elke
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170624/
https://ncbi.nlm.nih.gov/pubmed/24913448
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