A specific need for CRKL in p210(BCR-ABL)-induced transformation of mouse hematopoietic progenitors

CRKL (CRK-Like) is an adapter protein predominantly phosphorylated in cells that express the tyrosine kinase p210(BCR-ABL), the fusion product of a (9;22) chromosomal translocation causative for chronic myeloid leukemia (CML). It has been unclear, however, whether CRKL plays a functional role in p21...

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Main Authors: Seo, Ji-Heui, Wood, Lisa J., Agarwal, Anupriya, O’Hare, Thomas, Elsea, Collin R., Griswold, Ian J., Deininger, Michael W.N., Imamoto, Akira, Druker, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940946/
https://ncbi.nlm.nih.gov/pubmed/20807813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0607
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