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Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma
Ewing sarcoma (EwS) is an aggressive cancer characterized by chromosomal translocations generating fusions of the EWSR1 gene with ETS transcription factors (in 85% FLI1). EWSR1-FLI1 induces gene expression via binding to enhancer-like GGAA-microsatellites, whose activity correlates with the number o...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370763/ https://ncbi.nlm.nih.gov/pubmed/30741933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1372-0 |
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