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Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies

While sarcomas account for approximately 1% of malignant tumors of adults, they are particularly more common in children and adolescents affected by cancer. In contrast to malignancies that occur in later stages of life, childhood tumors, including sarcoma, are characterized by a striking paucity of...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Knott, Maximilian M. L., Hölting, Tilman L. B., Ohmura, Shunya, Kirchner, Thomas, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994515/
https://ncbi.nlm.nih.gov/pubmed/31970591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-019-09839-9
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