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Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies

While sarcomas account for approximately 1% of malignant tumors of adults, they are particularly more common in children and adolescents affected by cancer. In contrast to malignancies that occur in later stages of life, childhood tumors, including sarcoma, are characterized by a striking paucity of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Metastasis Rev
Prif Awduron: Knott, Maximilian M. L., Hölting, Tilman L. B., Ohmura, Shunya, Kirchner, Thomas, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994515/
https://ncbi.nlm.nih.gov/pubmed/31970591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-019-09839-9
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