The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

Lysophosphatidic acid (LPA) is a bioactive lipid promoting cancer metastasis. LPA activates a series of six G protein-coupled receptors (LPA(1-6)). While blockage of LPA(1) in vivo inhibits breast carcinoma metastasis, down-stream genes mediating LPA-induced metastasis have not been yet identified....

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Sahay, Debashish, Leblanc, Raphael, Grunewald, Thomas G. P., Ambatipudi, Srikant, Ribeiro, Johnny, Clézardin, Philippe, Peyruchaud, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653029/
https://ncbi.nlm.nih.gov/pubmed/26098771
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