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The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer
Lysophosphatidic acid (LPA) is a bioactive lipid promoting cancer metastasis. LPA activates a series of six G protein-coupled receptors (LPA(1-6)). While blockage of LPA(1) in vivo inhibits breast carcinoma metastasis, down-stream genes mediating LPA-induced metastasis have not been yet identified....
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出版年: | Oncotarget |
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主要な著者: | , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Impact Journals LLC
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653029/ https://ncbi.nlm.nih.gov/pubmed/26098771 |
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