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Autotaxin-β interaction with the cell surface via syndecan-4 impacts on cancer cell proliferation and metastasis

Autotaxin (ATX) promotes cancer cell metastasis through the production of lysophosphatidic acid (LPA). ATX binds to αvβ3 integrins controlling metastasis of breast cancer cells. We screened a series of cancer cell lines derived from diverse human and mouse solid tumors for the capacity of binding to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Leblanc, Raphael, Sahay, Debashish, Houssin, Audrey, Machuca-Gayet, Irma, Peyruchaud, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145688/
https://ncbi.nlm.nih.gov/pubmed/30237860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26039
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