Interaction of platelet-derived autotaxin with tumor integrin α(V)β(3) controls metastasis of breast cancer cells to bone

Autotaxin (ATX), through its lysophospholipase D activity controls physiological levels of lysophosphatidic acid (LPA) in blood. ATX is overexpressed in multiple types of cancers, and together with LPA generated during platelet activation promotes skeletal metastasis of breast cancer. However, the p...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Leblanc, Raphael, Lee, Sue-Chin, David, Marion, Bordet, Jean-Claude, Norman, Derek D., Patil, Renukadevi, Miller, Duane, Sahay, Debashish, Ribeiro, Johnny, Clézardin, Philippe, Tigyi, Gabor J., Peyruchaud, Olivier
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Platelets and Thrombopoiesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231421/
https://ncbi.nlm.nih.gov/pubmed/25277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568683
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