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Interaction of platelet-derived autotaxin with tumor integrin α(V)β(3) controls metastasis of breast cancer cells to bone

Autotaxin (ATX), through its lysophospholipase D activity controls physiological levels of lysophosphatidic acid (LPA) in blood. ATX is overexpressed in multiple types of cancers, and together with LPA generated during platelet activation promotes skeletal metastasis of breast cancer. However, the p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Leblanc, Raphael, Lee, Sue-Chin, David, Marion, Bordet, Jean-Claude, Norman, Derek D., Patil, Renukadevi, Miller, Duane, Sahay, Debashish, Ribeiro, Johnny, Clézardin, Philippe, Tigyi, Gabor J., Peyruchaud, Olivier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231421/
https://ncbi.nlm.nih.gov/pubmed/25277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568683
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