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Interaction of platelet-derived autotaxin with tumor integrin α(V)β(3) controls metastasis of breast cancer cells to bone
Autotaxin (ATX), through its lysophospholipase D activity controls physiological levels of lysophosphatidic acid (LPA) in blood. ATX is overexpressed in multiple types of cancers, and together with LPA generated during platelet activation promotes skeletal metastasis of breast cancer. However, the p...
Tallennettuna:
| Julkaisussa: | Blood |
|---|---|
| Päätekijät: | , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231421/ https://ncbi.nlm.nih.gov/pubmed/25277122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568683 |
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