Interaction of platelet-derived autotaxin with tumor integrin α(V)β(3) controls metastasis of breast cancer cells to bone

Autotaxin (ATX), through its lysophospholipase D activity controls physiological levels of lysophosphatidic acid (LPA) in blood. ATX is overexpressed in multiple types of cancers, and together with LPA generated during platelet activation promotes skeletal metastasis of breast cancer. However, the p...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Leblanc, Raphael, Lee, Sue-Chin, David, Marion, Bordet, Jean-Claude, Norman, Derek D., Patil, Renukadevi, Miller, Duane, Sahay, Debashish, Ribeiro, Johnny, Clézardin, Philippe, Tigyi, Gabor J., Peyruchaud, Olivier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2014
Konular:
Platelets and Thrombopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231421/
https://ncbi.nlm.nih.gov/pubmed/25277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568683
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