RET fusions observed in lung and colorectal cancers are sensitive to ponatinib

Por Gozgit, Joseph M., Chen, Tzu-Hsiu, Song, Youngchul, Wardwell, Scott, Wang, Frank, Cai, Jie, Li, Henry, Edgren, Henrik, Rivera, Victor M., Pritchard, Justin
Publicado no Oncotarget (2018)

Potent Activity of Ponatinib (AP24534) in Models of FLT3-Driven Acute Myeloid Leukemia and Other Hematologic Malignancies

Por Gozgit, Joseph M., Wong, Matthew J., Wardwell, Scott, Tyner, Jeffrey W., Loriaux, Marc M., Mohemmad, Qurish K., Narasimhan, Narayana I., Shakespeare, William C., Wang, Frank, Druker, Brian J., Clackson, Tim, Rivera, Victor M.
Publicado em 2011

Paralemmin-1 is over-expressed in estrogen-receptor positive breast cancers

Por Turk, Casey M, Fagan-Solis, Katerina D, Williams, Kristin E, Gozgit, Joseph M, Smith-Schneider, Sallie, Marconi, Sharon A, Otis, Christopher N, Crisi, Giovanna M, Anderton, Douglas L, Kilimann, Manfred W, Arcaro, Kathleen F
Publicado em 2012

Ponatinib in patients with refractory acute myeloid leukaemia: findings from a phase 1 study

Por Shah, Neil P., Talpaz, Moshe, Deininger, Michael W. N., Mauro, Michael J., Flinn, Ian W., Bixby, Dale, Lustgarten, Stephanie, Gozgit, Joseph M., Clackson, Tim, Turner, Christopher D., Haluska, Frank G., Kantarjian, Hagop, Cortes, Jorge E.
Publicado em 2013

Non-Amplified FGFR1 is a Growth Driver in Malignant Pleural Mesothelioma

Por Marek, Lindsay A., Hinz, Trista K., von Mässenhause, Anne, Olszewski, Kyle A., Kleczko, Emily K., Böhm, Diana, Weiser-Evans, Mary C., Nemenoff, Raphael A., Hoffmann, Hans, Warth, Arne, Gozgit, Joseph M., Perner, Sven, Heasley, Lynn E.
Publicado em 2014

Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients

Por Garner, Andrew P., Gozgit, Joseph M., Anjum, Rana, Vodala, Sadanand, Schrock, Alexa, Zhou, Tianjun, Serrano, Cesar, Eilers, Grant, Zhu, Meijun, Ketzer, Julia, Wardwell, Scott, Ning, Yaoyu, Song, Youngchul, Kohlmann, Anna, Wang, Frank, Clackson, Tim, Heinrich, Michael C., Fletcher, Jonathan A., Bauer, Sebastian, Rivera, Victor M.
Publicado no Clin Cancer Res (2014)

FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity Across All Lung Cancer Histologies

Por Wynes, Murry W., Hinz, Trista K., Gao, Dexiang, Martini, Michael, Marek, Lindsay A., Ware, Kathryn E., Edwards, Michael G., Böhm, Diana, Perner, Sven, Helfrich, Barbara A., Dziadziuszko, Rafal, Jassem, Jacek, Wojtylak, Szymon, Sejda, Aleksandra, Gozgit, Joseph M., Bunn, Paul A., Camidge, D. Ross, Tan, Aik-Choon, Hirsch, Fred R., Heasley, Lynn E.
Publicado em 2014

The JAK2 Inhibitor, AZD1480, Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Por Hedvat, Michael, Huszar, Dennis, Herrmann, Andreas, Gozgit, Joseph M., Schroeder, Anne, Sheehy, Adam, Buettner, Ralf, Proia, David, Kowolik, Claudia M., Xin, Hong, Armstrong, Brian, Bebernitz, Geraldine, Weng, Shaobu, Wang, Lin, Ye, Minwei, McEachern, Kristen, Chen, Huawei, Morosini, Deborah, Bell, Kirsten, Alimzhanov, Marat, Ioannidis, Stephanos, McCoon, Patricia, Cao, Zhu A., Yu, Hua, Jove, Richard, Zinda, Michael
Publicado em 2009