SUBSTRATE-DEPENDENT EFFECTS OF HUMAN ABCB1 CODING POLYMORPHISMS

Por Gow, Jason M., Hodges, Laura M., Chinn, Leslie W., Kroetz, Deanna L.
Publicado em 2008

Tenofovir Disoproxil Fumarate: Toxicity, Toxicokinetics, and Toxicogenomics Analysis After 13 Weeks of Oral Administration in Mice

Por Ng, Hanna H., Stock, Howard, Rausch, Linda, Bunin, Deborah, Wang, Abraham, Brill, Shirley, Gow, Jason, Mirsalis, Jon C.
Publicado no Int J Toxicol (2015)

Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

Por Hodges, Laura M., Markova, Svetlana M., Chinn, Leslie W., Gow, Jason M., Kroetz, Deanna L., Klein, Teri E., Altman, Russ B.
Publicado em 2011

Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteo...

Por Gow, Jason M., Tsuji, Wayne H., Williams, Gary J., Mytych, Daniel, Sciberras, David, Searle, Shawn L., Mant, Tim, Gibbs, John P.
Publicado no Arthritis Res Ther (2015)

Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains

Por Kelly, Libusha, Fukushima, Hisayo, Karchin, Rachel, Gow, Jason M, Chinn, Leslie W, Pieper, Ursula, Segal, Mark R, Kroetz, Deanna L, Sali, Andrej
Publicado em 2010

Response to “Predictable difficulty or difficulty to predict”

Por Kelly, Libusha, Fukushima, Hisayo, Karchin, Rachel, Gow, Jason M, Chinn, Leslie W, Pieper, Ursula, Segal, Mark R, Kroetz, Deanna L, Sali, Andrej
Publicado em 2011

FUNCTIONAL CHARACTERIZATION OF ABCC2 PROMOTER POLYMORPHISMS AND ALLELE SPECIFIC EXPRESSION

Por Nguyen, Tan D., Markova, Svetlana, Liu, Wanqing, Gow, Jason M., Baldwin, R. Michael, Habashian, Mahnoush, Relling, Mary V., Ratain, Mark J., Kroetz, Deanna L.
Publicado em 2012

Lead Optimization of 3-Carboxyl-4(1H)-Quinolones to Deliver Orally Bioavailable Antimalarials

Por Zhang, Yiqun, Clark, Julie A, Connelly, Michele C., Zhu, Fangyi, Min, Jaeki, Guiguemde, W. Armand, Pradhan, Anupam, Iyer, Lalitha, Furimsky, Anna, Gow, Jason, Parman, Toufan, El Mazouni, Farah, Phillips, Margaret A., Kyle, Dennis E., Mirsalis, Jon, Guy, R. Kiplin
Publicado em 2012

Lead Optimization of Anti-Malarial Propafenone Analogs

Por Lowes, David, Pradhan, Anupam, Iyer, Lalitha V., Parman, Toufan, Gow, Jason, Zhu, Fangyi, Furimsky, Anna, Lemoff, Andrew, Guiguemde, W. Armand, Sigal, Martina, Clark, Julie A., Wilson, Emily, Tang, Liang, Connelly, Michele C., DeRisi, Joseph L., Kyle, Dennis E., Mirsalis, Jon, Guy, R. Kiplin
Publicado no J Med Chem (2012)

Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression and Promoter Activity Predict Variation

Por Hesselson, Stephanie E., Matsson, Pär, Shima, James E., Fukushima, Hisayo, Yee, Sook Wah, Kobayashi, Yuya, Gow, Jason M., Ha, Connie, Ma, Benjamin, Poon, Annie, Johns, Susan J., Stryke, Doug, Castro, Richard A., Tahara, Harunobu, Choi, Ji Ha, Chen, Ligong, Picard, Nicolas, Sjödin, Elin, Roelofs, Maarke J. E., Ferrin, Thomas E., Myers, Richard, Kroetz, Deanna L., Kwok, Pui-Yan, Giacomini, Kathleen M.
Publicado em 2009

Clinical pharmacology of AMG 181, a gut-specific human anti-α(4)β(7) monoclonal antibody, for treating inflammatory bowel diseases

Por Pan, Wei-Jian, Köck, Kathleen, Rees, William A, Sullivan, Barbara A, Evangelista, Christine M, Yen, Mark, Andrews, Jane M, Radford-Smith, Graham L, Prince, Peter J, Reynhardt, Kaz O, Doherty, David R, Patel, Sonal K, Krill, Christine D, Zhou, Kefei, Shen, Jing, Smith, Lynn E, Gow, Jason M, Lee, Jonathan, Treacy, Anthony M, Yu, Zhigang, Platt, Virginia M, Borie, Dominic C
Publicado no Br J Clin Pharmacol (2014)