Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains

The human ATP-binding cassette (ABC) transporter superfamily consists of 48 integral membrane proteins that couple the action of ATP binding and hydrolysis to the transport of diverse substrates across cellular membranes. Defects in 18 transporters have been implicated in human disease. In hundreds...

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Detalhes bibliográficos
Main Authors: Kelly, Libusha, Fukushima, Hisayo, Karchin, Rachel, Gow, Jason M, Chinn, Leslie W, Pieper, Ursula, Segal, Mark R, Kroetz, Deanna L, Sali, Andrej
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005782/
https://ncbi.nlm.nih.gov/pubmed/20799350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.491
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