Dihydroquinazolinone Inhibitors of Proliferation of Blood and Liver Stage Malaria Parasites

Por Derbyshire, Emily R., Min, Jaeki, Guiguemde, W. Armand, Clark, Julie A., Connelly, Michele C., Magalhães, Andreia D., Guy, R. Kiplin, Clardy, Jon
Publicado em 2014

Optimization of Propafenone Analogues as Anti-Malarial Leads

Por Lowes, David J., Guiguemde, W. Armand, Connelly, Michele C., Zhu, Fangyi, Sigal, Martina S., Clark, Julie A., Lemoff, Andrew S., Derisi, Joseph L., Wilson, Emily B., Guy, R. Kiplin
Publicado em 2011

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogs for antimalarial activity

Por Hwang, Jong Yeon, Kawasuji, Takashi, Lowes, David J., Clark, Julie A., Connelly, Michele C., Zhu, Fangyi, Guiguemde, W. Armand, Sigal, Martina S., Wilson, Emily B., DeRisi, Joseph L., Guy, R. Kiplin
Publicado em 2011

Hit-to-Lead Studies for the Antimalarial Tetrahydroisoquinolone Carboxanilides()

Por Floyd, David M., Stein, Philip, Wang, Zheng, Liu, Jian, Castro, Steve, Clark, Julie A., Connelly, Michele, Zhu, Fangyi, Holbrook, Gloria, Matheny, Amy, Sigal, Martina S., Min, Jaeki, Dhinakaran, Rajkumar, Krishnan, Senthil, Bashyum, Sridevi, Knapp, Spencer, Guy, R. Kiplin
Publicado no J Med Chem (2016)

Lead Optimization of 3-Carboxyl-4(1H)-Quinolones to Deliver Orally Bioavailable Antimalarials

Por Zhang, Yiqun, Clark, Julie A, Connelly, Michele C., Zhu, Fangyi, Min, Jaeki, Guiguemde, W. Armand, Pradhan, Anupam, Iyer, Lalitha, Furimsky, Anna, Gow, Jason, Parman, Toufan, El Mazouni, Farah, Phillips, Margaret A., Kyle, Dennis E., Mirsalis, Jon, Guy, R. Kiplin
Publicado em 2012

Lead Optimization of Anti-Malarial Propafenone Analogs

Por Lowes, David, Pradhan, Anupam, Iyer, Lalitha V., Parman, Toufan, Gow, Jason, Zhu, Fangyi, Furimsky, Anna, Lemoff, Andrew, Guiguemde, W. Armand, Sigal, Martina, Clark, Julie A., Wilson, Emily, Tang, Liang, Connelly, Michele C., DeRisi, Joseph L., Kyle, Dennis E., Mirsalis, Jon, Guy, R. Kiplin
Publicado no J Med Chem (2012)

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

Por Jiménez-Díaz, María Belén, Ebert, Daniel, Salinas, Yandira, Pradhan, Anupam, Lehane, Adele M., Myrand-Lapierre, Marie-Eve, O’Loughlin, Kathleen G., Shackleford, David M., Justino de Almeida, Mariana, Carrillo, Angela K., Clark, Julie A., Dennis, Adelaide S. M., Diep, Jonathon, Deng, Xiaoyan, Duffy, Sandra, Endsley, Aaron N., Fedewa, Greg, Guiguemde, W. Armand, Gómez, María G., Holbrook, Gloria, Horst, Jeremy, Kim, Charles C., Liu, Jian, Lee, Marcus C. S., Matheny, Amy, Martínez, María Santos, Miller, Gregory, Rodríguez-Alejandre, Ane, Sanz, Laura, Sigal, Martina, Spillman, Natalie J., Stein, Philip D., Wang, Zheng, Zhu, Fangyi, Waterson, David, Knapp, Spencer, Shelat, Anang, Avery, Vicky M., Fidock, David A., Gamo, Francisco-Javier, Charman, Susan A., Mirsalis, Jon C., Ma, Hongshen, Ferrer, Santiago, Kirk, Kiaran, Angulo-Barturen, Iñigo, Kyle, Dennis E., DeRisi, Joseph L., Floyd, David M., Guy, R. Kiplin
Publicado no Proc Natl Acad Sci U S A (2014)