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Dihydroquinazolinone Inhibitors of Proliferation of Blood and Liver Stage Malaria Parasites

Drugs that target both the liver and blood stages of malaria will be needed to reduce the disease's substantial worldwide morbidity and mortality. Evaluation of a 259-member library of compounds that block proliferation of the blood stage of malaria revealed several scaffolds—dihydroquinazolino...

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Detalhes bibliográficos
Main Authors: Derbyshire, Emily R., Min, Jaeki, Guiguemde, W. Armand, Clark, Julie A., Connelly, Michele C., Magalhães, Andreia D., Guy, R. Kiplin, Clardy, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957893/
https://ncbi.nlm.nih.gov/pubmed/24366746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02148-13
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