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Dihydroquinazolinone Inhibitors of Proliferation of Blood and Liver Stage Malaria Parasites

Drugs that target both the liver and blood stages of malaria will be needed to reduce the disease's substantial worldwide morbidity and mortality. Evaluation of a 259-member library of compounds that block proliferation of the blood stage of malaria revealed several scaffolds—dihydroquinazolino...

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Autors principals: Derbyshire, Emily R., Min, Jaeki, Guiguemde, W. Armand, Clark, Julie A., Connelly, Michele C., Magalhães, Andreia D., Guy, R. Kiplin, Clardy, Jon
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957893/
https://ncbi.nlm.nih.gov/pubmed/24366746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02148-13
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