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Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Human malaria infection begins with a one-time asymptomatic liver stage followed by a cyclic symptomatic blood stage. All high-throughput malaria drug discovery efforts have focused on the cyclic blood stage, which has limited potential for the prophylaxis, transmission blocking, and eradication eff...

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Autori principali: Derbyshire, Emily R., Prudêncio, Miguel, Mota, Maria M., Clardy, Jon
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365169/
https://ncbi.nlm.nih.gov/pubmed/22586124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118370109
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