Discovery of Dual-Stage Malaria Inhibitors with New Targets

Malaria remains a major global health problem, with more than half of the world population at risk of contracting the disease and nearly a million deaths each year. Here, we report the discovery of inhibitors that target multiple stages of malaria parasite growth. To identify these inhibitors, we to...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Raphemot, Rene, Lafuente-Monasterio, Maria J., Gamo-Benito, Francisco Javier, Clardy, Jon, Derbyshire, Emily R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775961/
https://ncbi.nlm.nih.gov/pubmed/26666931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02110-15
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