Potent Plasmodium falciparum Gametocytocidal Activity of Diaminonaphthoquinones, Lead Antimalarial Chemotypes Identified in an Antimalarial Compound Screen

Forty percent of the world's population is threatened by malaria, which is caused by Plasmodium parasites and results in an estimated 200 million clinical cases and 650,000 deaths each year. Drug resistance has been reported for all commonly used antimalarials and has prompted screens to identi...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Tanaka, Takeshi Q, Guiguemde, W. Armand, Barnett, David S., Maron, Maxim I., Min, Jaeki, Connelly, Michele C., Suryadevara, Praveen Kumar, Guy, R. Kiplin, Williamson, Kim C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325765/
https://ncbi.nlm.nih.gov/pubmed/25512421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01930-13
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