Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease

Por Christodoulou, Danos C., Gorham, Joshua M., Herman, Daniel S.
Publicado em 2011

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis

Por Jiang, Jianming, Burgon, Patrick G., Wakimoto, Hiroko, Onoue, Kenji, Gorham, Joshua M., O’Meara, Caitlin C., Fomovsky, Gregory, McConnell, Bradley K., Lee, Richard T., Seidman, J. G., Seidman, Christine E.
Publicado no Proc Natl Acad Sci U S A (2015)

Molecular profiling of dilated cardiomyopathy that progresses to heart failure

Por Burke, Michael A., Chang, Stephen, Wakimoto, Hiroko, Gorham, Joshua M., Conner, David A., Christodoulou, Danos C., Parfenov, Michael G., DePalma, Steve R., Eminaga, Seda, Konno, Tetsuo, Seidman, Jonathan G., Seidman, Christine E.
Publicado no JCI Insight (2016)

Single-cell Resolution of Temporal Gene Expression during Heart Development

Por DeLaughter, Daniel M., Bick, Alexander G., Wakimoto, Hiroko, McKean, David, Gorham, Joshua M., Kathiriya, Irfan S., Hinson, John T., Homsy, Jason, Gray, Jesse, Pu, William, Bruneau, Benoit G., Seidman, J. G., Seidman, Christine E.
Publicado no Dev Cell (2016)

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy

Por Konno, Tetsuo, Chen, Dan, Wang, Libin, Wakimoto, Hiroko, Teekakirikul, Polakit, Nayor, Matthew, Kawana, Masataka, Eminaga, Seda, Gorham, Joshua M., Pandya, Kumar, Smithies, Oliver, Naya, Francisco J., Olson, Eric N., Seidman, J. G., Seidman, Christine E.
Publicado em 2010

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

Por Green, Eric M., Wakimoto, Hiroko, Anderson, Robert L., Evanchik, Marc J., Gorham, Joshua M., Harrison, Brooke C., Henze, Marcus, Kawas, Raja, Oslob, Johan D., Rodriguez, Hector M., Song, Yonghong, Wan, William, Leinwand, Leslie A., Spudich, James A., McDowell, Robert S., Seidman, J. G., Seidman, Christine E.
Publicado no Science (2016)

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β

Por Teekakirikul, Polakit, Eminaga, Seda, Toka, Okan, Alcalai, Ronny, Wang, Libin, Wakimoto, Hiroko, Nayor, Matthew, Konno, Tetsuo, Gorham, Joshua M., Wolf, Cordula M., Kim, Jae B., Schmitt, Joachim P., Molkentin, Jefferey D., Norris, Russell A., Tager, Andrew M., Hoffman, Stanley R., Markwald, Roger R., Seidman, Christine E., Seidman, Jonathan G.
Publicado em 2010

Dissecting spatio-temporal protein networks driving human heart development and related disorders

Por Lage, Kasper, Møllgård, Kjeld, Greenway, Steven, Wakimoto, Hiroko, Gorham, Joshua M, Workman, Christopher T, Bendsen, Eske, Hansen, Niclas T, Rigina, Olga, Roque, Francisco S, Wiese, Cornelia, Christoffels, Vincent M, Roberts, Amy E, Smoot, Leslie B, Pu, William T, Donahoe, Patricia K, Tommerup, Niels, Brunak, Søren, Seidman, Christine E, Seidman, Jonathan G, Larsen, Lars A
Publicado em 2010

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development

Por Lage, Kasper, Greenway, Steven C., Rosenfeld, Jill A., Wakimoto, Hiroko, Gorham, Joshua M., Segrè, Ayellet V., Roberts, Amy E., Smoot, Leslie B., Pu, William T., C. Pereira, Alexandre, Mesquita, Sonia M., Tommerup, Niels, Brunak, Søren, Ballif, Blake C., Shaffer, Lisa G., Donahoe, Patricia K., Daly, Mark J., Seidman, Jonathan G., Seidman, Christine E., Larsen, Lars A.
Publicado em 2012

Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice

Por Domenighetti, Andrea A., Chu, Pao-Hsien, Wu, Tongbin, Sheikh, Farah, Gokhin, David S., Guo, Ling T., Cui, Ziyou, Peter, Angela K., Christodoulou, Danos C., Parfenov, Michael G., Gorham, Joshua M., Li, Daniel Y., Banerjee, Indroneal, Lai, Xianyin, Witzmann, Frank A., Seidman, Christine E., Seidman, Jonathan G., Gomes, Aldrin V., Shelton, G. Diane, Lieber, Richard L., Chen, Ju
Publicado em 2014

5′RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy

Por Christodoulou, Danos C., Wakimoto, Hiroko, Onoue, Kenji, Eminaga, Seda, Gorham, Joshua M., DePalma, Steve R., Herman, Daniel S., Teekakirikul, Polakit, Conner, David A., McKean, David M., Domenighetti, Andrea A., Aboukhalil, Anton, Chang, Stephen, Srivastava, Gyan, McDonough, Barbara, De Jager, Philip L., Chen, Ju, Bulyk, Martha L., Muehlschlegel, Jochen D., Seidman, Christine E., Seidman, J.G.
Publicado em 2014

De Novo Copy Number Variants Identify New Genes and Loci in Isolated, Sporadic Tetralogy of Fallot

Por Greenway, Steven C, Pereira, Alexandre C, Lin, Jennifer C, DePalma, Steven R, Israel, Samuel J, Mesquita, Sonia M, Ergul, Emel, Conta, Jessie R, Korn, Joshua M, McCarroll, Steven A, Gorham, Joshua M, Gabriel, Stacey, Altshuler, David A, de Lourdes Quintanilla-Dieck, Maria, Artunduaga, Maria Alexandra, Eavey, Roland D, Plenge, Robert M, Shadick, Nancy A, Weinblatt, Michael E, De Jager, Philip L, Hafler, David A, Breitbart, Roger E, Seidman, J G, Seidman, Christine E
Publicado em 2009