Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis

Homozygous cardiac myosin binding protein C-deficient (Mybpc(t/t)) mice develop dramatic cardiac dilation shortly after birth; heart size increases almost twofold. We have investigated the mechanism of cardiac enlargement in these hearts. Throughout embryogenesis myocytes undergo cell division while...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Jiang, Jianming, Burgon, Patrick G., Wakimoto, Hiroko, Onoue, Kenji, Gorham, Joshua M., O’Meara, Caitlin C., Fomovsky, Gregory, McConnell, Bradley K., Lee, Richard T., Seidman, J. G., Seidman, Christine E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517252/
https://ncbi.nlm.nih.gov/pubmed/26153423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511004112
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