Role of cAMP and phosphodiesterase signaling in liver health and disease

por Wahlang, Banrida, McClain, Craig, Barve, Shirish, Gobejishvili, Leila
Publicado en Cell Signal (2018)

cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease

por Elnagdy, Mohamed, Barve, Shirish, McClain, Craig, Gobejishvili, Leila
Publicado en Biomolecules (2020)

Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

por Gobejishvili, Leila, Barve, Shirish, Joshi-Barve, Swati, McClain, Craig
Publicado 2008

Alcoholic Hepatitis: Steroids vs. Pentoxifylline

por Smart, Laura, Gobejishvili, Leila, Crittenden, Neil, Barve, Shirish, McClain, Craig J.
Publicado 2013

Liver Injury Assessment by Vetscan VS2 Analyzer and Most Frequently Used ALT/GTP Reagent

por Vatsalya, Vatsalya, Avila, Diana, Frimodig, Jane C., Barve, Shirish S, McClain, Craig J, Gobejishvili, Leila
Publicado en Gastroenterol Hepatol (Bartlesville) (2016)

Porphyromonas gingivalis as a Possible Risk Factor in the Development/Severity of Acute Alcoholic Hepatitis

por Zhou, Yun, Vatsalya, Vatsalya, Gobejishvili, Leila, Lamont, Richard J., McClain, Craig J., Feng, Wenke
Publicado en Hepatol Commun (2018)

Histone modifications and alcohol-induced liver disease: Are altered nutrients the missing link?

por Moghe, Akshata, Joshi-Barve, Swati, Ghare, Smita, Gobejishvili, Leila, Kirpich, Irina, McClain, Craig J, Barve, Shirish
Publicado 2011

Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis

por Avila, Diana V., Barker, David F., Zhang, JingWen, McClain, Craig J., Barve, Shirish, Gobejishvili, Leila
Publicado en J Pathol (2016)

Misoprostol modulates cytokine expression through a cAMP Pathway: potential therapeutic implication for liver disease

por Gobejishvili, Leila, Ghare, Smita, Khan, Rehan, Cambon, Alexander, Barker, David F., Barve, Shirish, McClain, Craig, Hill, Daniell
Publicado en Clin Immunol (2015)

Urinary acrolein metabolite levels in severe acute alcoholic hepatitis patients

por Vatsalya, Vatsalya, Kong, Maiying, Gobejishvili, Leila, Chen, Wei-Yang, Srivastava, Sanjay, Barve, Shirish, McClain, Craig, Joshi-Barve, Swati
Publicado en Am J Physiol Gastrointest Liver Physiol (2019)

Acrolein, a ubiquitous pollutant and lipid hydroperoxide, inhibits antiviral activity of interferon-alpha: relevance to Hepatitis C

por Joshi-Barve, Swati, Amancherla, Kiranmayi, Patil, Madhuvanti, Bhatnagar, Aruni, Mathews, Stephanie, Gobejishvili, Leila, Cave, Matthew, McClain, Craig, Barve, Shirish
Publicado 2009

Rolipram Attenuates Bile Duct Ligation–Induced Liver Injury in Rats: A Potential Pathogenic Role of PDE4

por Gobejishvili, Leila, Barve, Shirish, Breitkopf-Heinlein, Katja, Li, Yan, Zhang, JingWen, Avila, Diana V., Dooley, Steven, McClain, Craig J.
Publicado 2013

Focus on the Liver: Alcohol Use, Highly Active Antiretroviral Therapy, and Liver Disease In HIV-Infected Patients

por Barve, Shirish, Kapoor, Rama, Moghe, Akshata, Ramirez, Julio A., Eaton, John W., Gobejishvili, Leila, Joshi-Barve, Swati, McClain, Craig J.
Publicado 2010

Binge Ethanol-Induced HDAC3 Down-Regulates Cpt1α Expression Leading to Hepatic Steatosis and Injury

por Kirpich, Irina, Zhang, Jingwen, Gobejishvili, Leila, Kharebava, Giorgi, Barker, David, Ghare, Smita, Joshi-Barve, Swati, McClain, Craig J., Barve, Shirish
Publicado 2013

Binge Alcohol-Induced Microvesicular Liver Steatosis and Injury are Associated with Down-Regulation of Hepatic Hdac 1, 7, 9, 10, 11 and Up-Regulation of Hdac 3

por Kirpich, Irina, Ghare, Smita, Zhang, Jingwen, Gobejishvili, Leila, Kharebava, Giorgi, Barve, Swati Joshi, Barker, David, Moghe, Akshata, McClain, Craig, Barve, Shirish
Publicado en Alcohol Clin Exp Res (2012)

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease()

por Kirpich, Irina A., Gobejishvili, Leila N., Homme, Marjorie Bon, Waigel, Sabine, Cave, Matt, Arteel, Gavin, Barve, Shirish S., McClain, Craig J., Deaciuc, Ion V.
Publicado 2010

Coordinated histone H3 methylation and acetylation regulates physiologic and pathologic Fas Ligand gene expression in human CD4+ T cells

por Ghare, Smita S., Joshi-Barve, Swati, Moghe, Akshata, Patil, Madhuvanti, Barker, David F., Gobejishvili, Leila, Brock, Guy N., Cave, Matthew, McClain, Craig J., Barve, Shirish S.
Publicado en J Immunol (2014)

Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation

por Avila, Diana V, Myers, Scott A, Zhang, JingWen, Kharebava, Giorgi, McClain, Craig J, Kim, Hee-Yong, Whittemore, Scott R, Gobejishvili, Leila, Barve, Shirish
Publicado en Neuropharmacology (2017)

Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury

por Donde, Hridgandh, Ghare, Smita, Joshi-Barve, Swati, Zhang, JingWen, Vadhanam, Manicka V., Gobejishvili, Leila, Lorkiewicz, Pawel, Srivastava, Sanjay, McClain, Craig J., Barve, Shirish
Publicado en Cell Mol Gastroenterol Hepatol (2019)

Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia

por Myers, Scott A., Gobejishvili, Leila, Ohri, Sujata Saraswat, Wilson, C. Garrett, Andres, Kariena R., Riegler, Amberly S., Donde, Hridgandh, Joshi-Barve, Swati, Barve, Shirish, Whittemore, Scott R.
Publicado en Neurobiol Dis (2018)