Binge Alcohol-Induced Microvesicular Liver Steatosis and Injury are Associated with Down-Regulation of Hepatic Hdac 1, 7, 9, 10, 11 and Up-Regulation of Hdac 3

BACKGROUND: Binge, as well as chronic, alcohol consumption affects global histone acetylation leading to changes in gene expression. It is becoming increasingly evident that these histone associated epigenetic modifications play an important role in the development of alcohol-mediated hepatic injury...

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Publicat a:Alcohol Clin Exp Res
Autors principals: Kirpich, Irina, Ghare, Smita, Zhang, Jingwen, Gobejishvili, Leila, Kharebava, Giorgi, Barve, Swati Joshi, Barker, David, Moghe, Akshata, McClain, Craig, Barve, Shirish
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867116/
https://ncbi.nlm.nih.gov/pubmed/22375794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2012.01751.x
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