Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

Increased plasma and hepatic TNF-α expression is well documented in patients with alcoholic hepatitis and is implicated in the pathogenesis of alcoholic liver disease. We have previously shown that monocytes from patients with alcoholic hepatitis show increased constitutive and LPS-induced NF-κB act...

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Detalles Bibliográficos
Main Authors: Gobejishvili, Leila, Barve, Shirish, Joshi-Barve, Swati, McClain, Craig
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
Assuntos:
Inflammation/Immunity/Mediators
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575909/
https://ncbi.nlm.nih.gov/pubmed/18687753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90232.2008
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