Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

Increased plasma and hepatic TNF-α expression is well documented in patients with alcoholic hepatitis and is implicated in the pathogenesis of alcoholic liver disease. We have previously shown that monocytes from patients with alcoholic hepatitis show increased constitutive and LPS-induced NF-κB act...

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Hlavní autoři: Gobejishvili, Leila, Barve, Shirish, Joshi-Barve, Swati, McClain, Craig
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
Témata:
Inflammation/Immunity/Mediators
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575909/
https://ncbi.nlm.nih.gov/pubmed/18687753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90232.2008
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