Myeloproliferative disorders

Por Levine, Ross L., Gilliland, D. Gary
Publicado em 2008

EGFR Inhibition in Non-Small Cell Lung Cancer: Resistance, Once Again, Rears Its Ugly Head

Por Clark, Jennifer, Cools, Jan, Gilliland, D. Gary
Publicado em 2005

The leukemic stem cell niche: current concepts and therapeutic opportunities

Por Lane, Steven W., Scadden, David T., Gilliland, D. Gary
Publicado em 2009

Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

Por Morgan, Kelly, Kharas, Michael, Dzierzak, Elaine, Gilliland, D. Gary
Publicado em 2008

A progenitor cell origin of myeloid malignancies

Por Haeno, Hiroshi, Levine, Ross L., Gilliland, D. Gary, Michor, Franziska
Publicado em 2009

Socs-1 Inhibits TEL-JAK2-Mediated Transformation of Hematopoietic Cells through Inhibition of JAK2 Kinase Activity and Induction of Proteasome-Mediated Degradation

Por Frantsve, Julie, Schwaller, Juerg, Sternberg, David W., Kutok, Jeffery, Gilliland, D. Gary
Publicado em 2001

Uniform sensitivity of FLT3 activation loop mutants to the tyrosine kinase inhibitor midostaurin

Por Barry, Elly V., Clark, Jennifer J., Cools, Jan, Roesel, Johannes, Gilliland, D. Gary
Publicado em 2007

The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase-d...

Por Carroll, Martin, Tomasson, Michael H., Barker, George F., Golub, Todd R., Gilliland, D. Gary
Publicado em 1996

Expression of Jak2V617F causes a polycythemia vera–like disease with associated myelofibrosis in a murine bone marrow transplant model

Por Wernig, Gerlinde, Mercher, Thomas, Okabe, Rachel, Levine, Ross L., Lee, Benjamin H., Gilliland, D. Gary
Publicado em 2006

Systematic Genomic Screen for Tyrosine Kinase Mutations in CLL

Por Brown, Jennifer R, Levine, Ross L., Thompson, Christina, Basile, Gabrielle, Gilliland, D Gary, Freedman, Arnold S
Publicado em 2008

Signal transduction and transforming properties of the TEL–TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

Por Liu, Qing, Schwaller, Juerg, Kutok, Jeffery, Cain, Danielle, Aster, Jon C., Williams, Ifor R., Gilliland, D.Gary
Publicado em 2000

Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation

Por Lu, Xiaohui, Levine, Ross, Tong, Wei, Wernig, Gerlinde, Pikman, Yana, Zarnegar, Sara, Gilliland, D. Gary, Lodish, Harvey
Publicado em 2005

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412

Por Growney, Joseph D., Clark, Jennifer J., Adelsperger, Jennifer, Stone, Richard, Fabbro, Doriano, Griffin, James D., Gilliland, D. Gary
Publicado em 2005

X-inactivation–based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a sub...

Por Levine, Ross L., Belisle, Claude, Wadleigh, Martha, Zahrieh, David, Lee, Stephanie, Chagnon, Pierre, Gilliland, D. Gary, Busque, Lambert
Publicado em 2006

Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD

Por Rocnik, Jennifer L., Okabe, Rachel, Yu, Jin-Chen, Lee, Benjamin H., Giese, Neill, Schenkein, David P., Gilliland, D. Gary
Publicado em 2006

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

Por Kharas, Michael G., Okabe, Rachel, Ganis, Jared J., Gozo, Maricel, Khandan, Tulasi, Paktinat, Mahnaz, Gilliland, D. Gary, Gritsman, Kira
Publicado em 2010

Constitutively activated FGFR3 mutants signal through PLCγ-dependent and -independent pathways for hematopoietic transformation

Por Chen, Jing, Williams, Ifor R., Lee, Benjamin H., Duclos, Nicole, Huntly, Brian J. P., Donoghue, Daniel J., Gilliland, D. Gary
Publicado em 2005

Ott1 (Rbm15) Is Essential for Placental Vascular Branching Morphogenesis and Embryonic Development of the Heart and Spleen

Por Raffel, Glen D., Chu, Gerald C., Jesneck, Jonathan L., Cullen, Dana E., Bronson, Roderick T., Bernard, Olivier A., Gilliland, D. Gary
Publicado em 2009

Stable expression of small interfering RNA sensitizes TEL-PDGFβR to inhibition with imatinib or rapamycin

Por Chen, Jing, Wall, Nathan R., Kocher, Kerry, Duclos, Nicole, Fabbro, Doriano, Neuberg, Donna, Griffin, James D., Shi, Yang, Gilliland, D. Gary
Publicado em 2004

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Por Raffel, Glen D., Mercher, Thomas, Shigematsu, Hirokazu, Williams, Ifor R., Cullen, Dana E., Akashi, Koichi, Bernard, Olivier A., Gilliland, D. Gary
Publicado em 2007