Myeloproliferative disorders

Autor Levine, Ross L., Gilliland, D. Gary
Vydáno 2008

EGFR Inhibition in Non-Small Cell Lung Cancer: Resistance, Once Again, Rears Its Ugly Head

Autor Clark, Jennifer, Cools, Jan, Gilliland, D. Gary
Vydáno 2005

The leukemic stem cell niche: current concepts and therapeutic opportunities

Autor Lane, Steven W., Scadden, David T., Gilliland, D. Gary
Vydáno 2009

Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

Autor Morgan, Kelly, Kharas, Michael, Dzierzak, Elaine, Gilliland, D. Gary
Vydáno 2008

A progenitor cell origin of myeloid malignancies

Autor Haeno, Hiroshi, Levine, Ross L., Gilliland, D. Gary, Michor, Franziska
Vydáno 2009

Socs-1 Inhibits TEL-JAK2-Mediated Transformation of Hematopoietic Cells through Inhibition of JAK2 Kinase Activity and Induction of Proteasome-Mediated Degradation

Autor Frantsve, Julie, Schwaller, Juerg, Sternberg, David W., Kutok, Jeffery, Gilliland, D. Gary
Vydáno 2001

Uniform sensitivity of FLT3 activation loop mutants to the tyrosine kinase inhibitor midostaurin

Autor Barry, Elly V., Clark, Jennifer J., Cools, Jan, Roesel, Johannes, Gilliland, D. Gary
Vydáno 2007

The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase-d...

Autor Carroll, Martin, Tomasson, Michael H., Barker, George F., Golub, Todd R., Gilliland, D. Gary
Vydáno 1996

Expression of Jak2V617F causes a polycythemia vera–like disease with associated myelofibrosis in a murine bone marrow transplant model

Autor Wernig, Gerlinde, Mercher, Thomas, Okabe, Rachel, Levine, Ross L., Lee, Benjamin H., Gilliland, D. Gary
Vydáno 2006

Systematic Genomic Screen for Tyrosine Kinase Mutations in CLL

Autor Brown, Jennifer R, Levine, Ross L., Thompson, Christina, Basile, Gabrielle, Gilliland, D Gary, Freedman, Arnold S
Vydáno 2008

Signal transduction and transforming properties of the TEL–TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

Autor Liu, Qing, Schwaller, Juerg, Kutok, Jeffery, Cain, Danielle, Aster, Jon C., Williams, Ifor R., Gilliland, D.Gary
Vydáno 2000

Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation

Autor Lu, Xiaohui, Levine, Ross, Tong, Wei, Wernig, Gerlinde, Pikman, Yana, Zarnegar, Sara, Gilliland, D. Gary, Lodish, Harvey
Vydáno 2005

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412

Autor Growney, Joseph D., Clark, Jennifer J., Adelsperger, Jennifer, Stone, Richard, Fabbro, Doriano, Griffin, James D., Gilliland, D. Gary
Vydáno 2005

X-inactivation–based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a sub...

Autor Levine, Ross L., Belisle, Claude, Wadleigh, Martha, Zahrieh, David, Lee, Stephanie, Chagnon, Pierre, Gilliland, D. Gary, Busque, Lambert
Vydáno 2006

Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD

Autor Rocnik, Jennifer L., Okabe, Rachel, Yu, Jin-Chen, Lee, Benjamin H., Giese, Neill, Schenkein, David P., Gilliland, D. Gary
Vydáno 2006

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

Autor Kharas, Michael G., Okabe, Rachel, Ganis, Jared J., Gozo, Maricel, Khandan, Tulasi, Paktinat, Mahnaz, Gilliland, D. Gary, Gritsman, Kira
Vydáno 2010

Constitutively activated FGFR3 mutants signal through PLCγ-dependent and -independent pathways for hematopoietic transformation

Autor Chen, Jing, Williams, Ifor R., Lee, Benjamin H., Duclos, Nicole, Huntly, Brian J. P., Donoghue, Daniel J., Gilliland, D. Gary
Vydáno 2005

Ott1 (Rbm15) Is Essential for Placental Vascular Branching Morphogenesis and Embryonic Development of the Heart and Spleen

Autor Raffel, Glen D., Chu, Gerald C., Jesneck, Jonathan L., Cullen, Dana E., Bronson, Roderick T., Bernard, Olivier A., Gilliland, D. Gary
Vydáno 2009

Stable expression of small interfering RNA sensitizes TEL-PDGFβR to inhibition with imatinib or rapamycin

Autor Chen, Jing, Wall, Nathan R., Kocher, Kerry, Duclos, Nicole, Fabbro, Doriano, Neuberg, Donna, Griffin, James D., Shi, Yang, Gilliland, D. Gary
Vydáno 2004

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Autor Raffel, Glen D., Mercher, Thomas, Shigematsu, Hirokazu, Williams, Ifor R., Cullen, Dana E., Akashi, Koichi, Bernard, Olivier A., Gilliland, D. Gary
Vydáno 2007