Formation and Propagation of Tau Oligomeric Seeds

Por Gerson, Julia E., Kayed, Rakez
Publicado em 2013

Potential Mechanisms and Implications for the Formation of Tau Oligomeric Strains

Por Gerson, Julia E., Mudher, Amrit, Kayed, Rakez
Publicado no Crit Rev Biochem Mol Biol (2016)

The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration

Por Deger, Jennifer M, Gerson, Julia E, Kayed, Rakez
Publicado no Aging Cell (2015)

Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing

Por Mennenga, Sarah E., Gerson, Julia E., Dunckley, Travis, Bimonte-Nelson, Heather A.
Publicado no Physiol Behav (2014)

α-Synuclein Oligomers Induce a Unique Toxic Tau Strain

Por Castillo-Carranza, Diana L., Guerrero-Muñoz, Marcos J., Sengupta, Urmi, Gerson, Julia E., Kayed, Rakez
Publicado no Biol Psychiatry (2018)

Characterization of tau oligomeric seeds in progressive supranuclear palsy

Por Gerson, Julia E, Sengupta, Urmi, Lasagna-Reeves, Cristian A, Guerrero-Muñoz, Marcos J, Troncoso, Juan, Kayed, Rakez
Publicado no Acta Neuropathol Commun (2014)

Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy

Por Gerson, Julia E., Farmer, Kathleen M., Henson, Natalie, Castillo-Carranza, Diana L., Carretero Murillo, Mariana, Sengupta, Urmi, Barrett, Alan, Kayed, Rakez
Publicado no Mol Neurodegener (2018)

Nature-inspired design and evolution of anti-amyloid antibodies

Por Julian, Mark C., Rabia, Lilia A., Desai, Alec A., Arsiwala, Ammar, Gerson, Julia E., Paulson, Henry L., Kane, Ravi S., Tessier, Peter M.
Publicado no J Biol Chem (2019)

The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes

Por Lasagna-Reeves, Cristian A, Sengupta, Urmi, Castillo-Carranza, Diana, Gerson, Julia E, Guerrero-Munoz, Marcos, Troncoso, Juan C, Jackson, George R, Kayed, Rakez
Publicado no Acta Neuropathol Commun (2014)

AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation

Por Ha, Yonju, Liu, Wei, Liu, Hua, Zhu, Shuang, Xia, Fan, Gerson, Julia E., Azhar, Nisha A., Tilton, Ronald G., Motamedi, Massoud, Kayed, Rakez, Zhang, Wenbo
Publicado no Invest Ophthalmol Vis Sci (2018)

Understanding the cognitive impact of the contraceptive estrogen Ethinyl Estradiol: tonic and cyclic administration impairs memory, and performance correlates with basal forebrain...

Por Mennenga, Sarah E., Gerson, Julia E., Koebele, Stephanie V., Kingston, Melissa L., Tsang, Candy W.S., Engler-Chiurazzi, Elizabeth B., Baxter, Leslie C., Bimonte-Nelson, Heather A.
Publicado no Psychoneuroendocrinology (2015)

Ubiquilin-2 differentially regulates polyglutamine disease proteins

Por Gerson, Julia E, Safren, Nathaniel, Fischer, Svetlana, Patel, Ronak, Crowley, Emily V, Welday, Jacqueline P, Windle, Alexandra K, Barmada, Sami, Paulson, Henry L, Sharkey, Lisa M
Publicado no Hum Mol Genet (2020)

Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

Por Gerson, Julia E., Linton, Hunter, Xing, Jiazheng, Sutter, Alexandra B., Kakos, Fayth S., Ryou, Jaimie, Liggans, Nyjerus, Sharkey, Lisa M., Safren, Nathaniel, Paulson, Henry L., Ivanova, Magdalena I.
Publicado no Sci Rep (2021)

High serum androstenedione levels correlate with impaired memory in the surgically menopausal rat: a replication and new findings

Por Camp, Bryan W., Gerson, Julia E., Tsang, Candy Wing S., Villa, Stephanie R., Acosta, Jazmin I., Braden, B. Blair, Hoffman, Ann N., Conrad, Cheryl D., Bimonte-Nelson, Heather A.
Publicado em 2012

Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases

Por Nilson, Ashley N., English, Kelsey C., Gerson, Julia E., Barton Whittle, T., Nicolas Crain, C., Xue, Judy, Sengupta, Urmi, Castillo-Carranza, Diana L., Zhang, Wenbo, Gupta, Praveena, Kayed, Rakez
Publicado no J Alzheimers Dis (2016)

Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

Por Castillo-Carranza, Diana L., Sengupta, Urmi, Guerrero-Muñoz, Marcos J., Lasagna-Reeves, Cristian A., Gerson, Julia E., Singh, Gurpreet, Estes, D. Mark, Barrett, Alan D. T., Dineley, Kelly T., Jackson, George R., Kayed, Rakez
Publicado no J Neurosci (2014)

Modeling UBQLN2-mediated neurodegenerative disease in mice: shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered pr...

Por Sharkey, Lisa M., Sandoval-Pistorius, Stephanie S., Moore, Shannon J., Gerson, Julia E., Komlo, Robert, Fischer, Svetlana, Negron-Rios, Keyshla Y., Crowley, Emily V., Padron, Francisco, Patel, Ronak, Murphy, Geoffrey G., Paulson, Henry L.
Publicado no Neurobiol Dis (2020)

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies

Por Castillo-Carranza, Diana L, Nilson, Ashley N, Van Skike, Candice E, Jahrling, Jordan B, Patel, Kishan, Garach, Prajesh, Gerson, Julia E, Sengupta, Urmi, Abisambra, Jose, Nelson, Peter, Troncoso, Juan, Ungvari, Zoltan, Galvan, Veronica, Kayed, Rakez
Publicado no Aging Dis (2017)

Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly

Por Sharkey, Lisa M., Safren, Nathaniel, Pithadia, Amit S., Gerson, Julia E., Dulchavsky, Mark, Fischer, Svetlana, Patel, Ronak, Lantis, Gabrielle, Ashraf, Naila, Kim, John H., Meliki, Alia, Minakawa, Eiko N., Barmada, Sami J., Ivanova, Magdalena I., Paulson, Henry L.
Publicado no Proc Natl Acad Sci U S A (2018)

Navigating to new frontiers in behavioral neuroscience: traditional neuropsychological tests predict human performance on a rodent-inspired radial-arm maze

Por Mennenga, Sarah E., Baxter, Leslie C., Grunfeld, Itamar S., Brewer, Gene A., Aiken, Leona S., Engler-Chiurazzi, Elizabeth B., Camp, Bryan W., Acosta, Jazmin I., Braden, B. Blair, Schaefer, Keley R., Gerson, Julia E., Lavery, Courtney N., Tsang, Candy W. S., Hewitt, Lauren T., Kingston, Melissa L., Koebele, Stephanie V., Patten, K. Jakob, Ball, B. Hunter, McBeath, Michael K., Bimonte-Nelson, Heather A.
Publicado em 2014