Ubiquilin-2 differentially regulates polyglutamine disease proteins

Divergent protein context helps explain why polyglutamine expansion diseases differ clinically and pathologically. This heterogeneity may also extend to how polyglutamine disease proteins are handled by cellular pathways of proteostasis. Studies suggest, for example, that the ubiquitin-proteasome sh...

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Библиографические подробности
Опубликовано в: :Hum Mol Genet
Главные авторы: Gerson, Julia E, Safren, Nathaniel, Fischer, Svetlana, Patel, Ronak, Crowley, Emily V, Welday, Jacqueline P, Windle, Alexandra K, Barmada, Sami, Paulson, Henry L, Sharkey, Lisa M
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
1 General Article - US Office
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471500/
https://ncbi.nlm.nih.gov/pubmed/32681165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa152
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