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Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins
Previously we showed that overexpression of ubiquilin reduces protein aggregates and toxicity of expanded polyglutamine proteins. Here, we investigated the mechanism of ubiquilin's protective effect. Immunofluorescence microscopy and immunoprecipitation studies indicated that ubiquilin colocali...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2062524/ https://ncbi.nlm.nih.gov/pubmed/17603015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.097 |
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