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Ubiquilin overexpression reduces GFP-polyalanine-induced protein aggregates and toxicity

Several human disorders are associated with an increase in a continuous stretch of alanine amino acids in proteins. These so called polyalanine expansion diseases share many similarities with polyglutamine-related disorders, including a length-dependent reiteration of amino acid induction of protein...

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Detalhes bibliográficos
Main Authors: Wang, Hongmin, Monteiro, Mervyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002572/
https://ncbi.nlm.nih.gov/pubmed/17490645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.04.006
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