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Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy
BACKGROUND: We have evaluated the efficacy of targeting the toxic, oligomeric form of tau protein by passive immunotherapy in a mouse model of synucleinopathy. Parkinson’s disease and Lewy body dementia are two of the most common neurodegenerative disorders and are primarily characterized by the acc...
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| Pubblicato in: | Mol Neurodegener |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856311/ https://ncbi.nlm.nih.gov/pubmed/29544548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0245-9 |
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