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α-Synuclein Oligomers Induce a Unique Toxic Tau Strain

BACKGROUND: The coexistence of α-synuclein and tau aggregates in several neurodegenerative disorders, including Parkinson’s disease and Alzheimer’s disease, raises the possibility that a seeding mechanism is involved in disease progression. METHODS: To further investigate the role of α-synuclein in...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Psychiatry
Hauptverfasser: Castillo-Carranza, Diana L., Guerrero-Muñoz, Marcos J., Sengupta, Urmi, Gerson, Julia E., Kayed, Rakez
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201292/
https://ncbi.nlm.nih.gov/pubmed/29478699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.12.018
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