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Design of Metastable β-Sheet Oligomers from Natively Unstructured Peptide

[Image: see text] Amyloid oligomers represent the primary pathological species for neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Toxic oligomers are formed by many different proteins and peptides, but their polydispersity makes them highly dynamic and heterogeneous. One wa...

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Detalhes bibliográficos
Main Authors: Guerrero-Muñoz, Marcos J., Castillo-Carranza, Diana L., Sengupta, Urmi, White, Mark A., Kayed, Rakez
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867962/
https://ncbi.nlm.nih.gov/pubmed/24106878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001395
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