Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

Neurofibrillary tangles (NFTs) are a pathological hallmark of Alzheimer's disease (AD); however, the relationship between NFTs and disease progression remains controversial. Analyses of tau animal models suggest that phenotypes coincide with accumulation of soluble aggregated tau species but no...

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Главные авторы: Lasagna-Reeves, Cristian A., Castillo-Carranza, Diana L., Sengupta, Urmi, Sarmiento, Jose, Troncoso, Juan, Jackson, George R., Kayed, Rakez
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2012
Предметы:
Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046102/
https://ncbi.nlm.nih.gov/pubmed/22253473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-199851
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