Design of Metastable β-Sheet Oligomers from Natively Unstructured Peptide

[Image: see text] Amyloid oligomers represent the primary pathological species for neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Toxic oligomers are formed by many different proteins and peptides, but their polydispersity makes them highly dynamic and heterogeneous. One wa...

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Bibliographic Details
Main Authors: Guerrero-Muñoz, Marcos J., Castillo-Carranza, Diana L., Sengupta, Urmi, White, Mark A., Kayed, Rakez
Format: Artigo
Language:Inglês
Published: American Chemical Society 2013
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867962/
https://ncbi.nlm.nih.gov/pubmed/24106878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001395
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