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Design of Metastable β-Sheet Oligomers from Natively Unstructured Peptide

[Image: see text] Amyloid oligomers represent the primary pathological species for neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Toxic oligomers are formed by many different proteins and peptides, but their polydispersity makes them highly dynamic and heterogeneous. One wa...

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Autores principales: Guerrero-Muñoz, Marcos J., Castillo-Carranza, Diana L., Sengupta, Urmi, White, Mark A., Kayed, Rakez
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2013
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867962/
https://ncbi.nlm.nih.gov/pubmed/24106878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001395
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