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The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration

Various neurodegenerative diseases are characterized by the accumulation of amyloidogenic proteins such as tau, α-synuclein, and amyloid-β. Prior to the formation of these stable aggregates, intermediate species of the respective proteins—oligomers—appear. Recently acquired data have shown that olig...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Deger, Jennifer M, Gerson, Julia E, Kayed, Rakez
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568959/
https://ncbi.nlm.nih.gov/pubmed/26053162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12359
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