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Potential Mechanisms and Implications for the Formation of Tau Oligomeric Strains

The culmination of many years of increasing research into the toxicity of tau aggregation in neurodegenerative disease has led to the consensus that soluble, oligomeric forms of tau are likely the most toxic entities in disease. While tauopathies overlap in the presence of tau pathology, each diseas...

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Pubblicato in:Crit Rev Biochem Mol Biol
Autori principali: Gerson, Julia E., Mudher, Amrit, Kayed, Rakez
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285467/
https://ncbi.nlm.nih.gov/pubmed/27650389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2016.1226251
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