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Modulating disease-relevant tau oligomeric strains by small molecules

The pathological aggregation of tau plays an important role in Alzheimer's disease and many other related neurodegenerative diseases, collectively referred to as tauopathies. Recent evidence has demonstrated that tau oligomers, small and soluble prefibrillar aggregates, are highly toxic due to...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Lo Cascio, Filippa, Garcia, Stephanie, Montalbano, Mauro, Puangmalai, Nicha, McAllen, Salome, Pace, Andrea, Palumbo Piccionello, Antonio, Kayed, Rakez
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606668/
https://ncbi.nlm.nih.gov/pubmed/32737202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014630
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