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Modulating disease-relevant tau oligomeric strains by small molecules
The pathological aggregation of tau plays an important role in Alzheimer's disease and many other related neurodegenerative diseases, collectively referred to as tauopathies. Recent evidence has demonstrated that tau oligomers, small and soluble prefibrillar aggregates, are highly toxic due to...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606668/ https://ncbi.nlm.nih.gov/pubmed/32737202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014630 |
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