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Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration

The exact mechanisms leading to neurodegeneration in Alzheimer's disease (AD) and other tauopathies are not yet entirely understood. However, it is known that several RNA‐binding proteins (RBPs) form toxic aggregates and also interact with tau in such granules in tauopathies, including AD. The...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Montalbano, Mauro, McAllen, Salome, Sengupta, Urmi, Puangmalai, Nicha, Bhatt, Nemil, Ellsworth, Anna, Kayed, Rakez
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826126/
https://ncbi.nlm.nih.gov/pubmed/31532069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13035
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