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Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration

The exact mechanisms leading to neurodegeneration in Alzheimer's disease (AD) and other tauopathies are not yet entirely understood. However, it is known that several RNA‐binding proteins (RBPs) form toxic aggregates and also interact with tau in such granules in tauopathies, including AD. The...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Montalbano, Mauro, McAllen, Salome, Sengupta, Urmi, Puangmalai, Nicha, Bhatt, Nemil, Ellsworth, Anna, Kayed, Rakez
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826126/
https://ncbi.nlm.nih.gov/pubmed/31532069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13035
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