Dendritic cells, the T cell-inflamed tumor microenvironment and immunotherapy treatment response

door Garris, Christopher S., Luke, Jason J.
Gepubliceerd in Clin Cancer Res (2020)

Cancer metastasis as a non-healing wound

door Deyell, Matthew, Garris, Christopher S., Laughney, Ashley M.
Gepubliceerd in Br J Cancer (2021)

Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond

door Garris, Christopher S, Blaho, Victoria A, Hla, Timothy, Han, May H
Gepubliceerd in 2014

Recording the wild lives of immune cells

door Pittet, Mikael J., Garris, Christopher S., Arlauckas, Sean P., Weissleder, Ralph
Gepubliceerd in Sci Immunol (2018)

Intravesical dendritic cell targeting with Fc-enhanced CD40 agonistic antibodies induces durable bladder cancer immunity

door Garris, Christopher S., Wong, Jeffrey L., Ravetch, Jeffrey V., Knorr, David A.
Gepubliceerd in Sci Transl Med (2021)

Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy

door Rodell, Christopher B., Ahmed, Maaz S., Garris, Christopher S., Pittet, Mikael J., Weissleder, Ralph
Gepubliceerd in Theranostics (2019)

Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to FTY720 during neuroinflammation

door Tsai, Hsing-Chuan, Huang, Yingxiang, Garris, Christopher S., Moreno, Monica A., Griffin, Christina W., Han, May H.
Gepubliceerd in JCI Insight (2016)

Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation

door Lan, Yuk Yuen, Heather, James M., Eisenhaure, Thomas, Garris, Christopher Stuart, Lieb, David, Raychowdhury, Raktima, Hacohen, Nir
Gepubliceerd in Aging Cell (2019)

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

door Cuccarese, Michael F., Dubach, J. Matthew, Pfirschke, Christina, Engblom, Camilla, Garris, Christopher, Miller, Miles A., Pittet, Mikael J., Weissleder, Ralph
Gepubliceerd in Nat Commun (2017)

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

door Rodell, Christopher B., Arlauckas, Sean P., Cuccarese, Michael F., Garris, Christopher S., Li, Ran, Ahmed, Maaz S., Kohler, Rainer H., Pittet, Mikael J., Weissleder, Ralph
Gepubliceerd in Nat Biomed Eng (2018)

PF4 promotes platelet production and lung cancer growth

door Pucci, Ferdinando, Rickelt, Steffen, Newton, Andita P., Garris, Christopher, Nunes, Ernesto, Evavold, Charles, Pfirschke, Christina, Engblom, Camilla, Mino-Kenudson, Mari, Hynes, Richard O., Weissleder, Ralph, Pittet, Mikael J
Gepubliceerd in Cell Rep (2016)

LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects

door Liao, Hsin-Wei, Garris, Christopher, Pfirschke, Christina, Rickelt, Steffen, Arlauckas, Sean, Siwicki, Marie, Kohler, Rainer H., Weissleder, Ralph, Sundvold-Gjerstad, Vibeke, Sveinbjørnsson, Baldur, Rekdal, Øystein, Pittet, Mikael J.
Gepubliceerd in Cell Stress (2019)

In vivo imaging reveals a tumor-associated macrophage mediated resistance pathway in anti-PD-1 therapy

door Arlauckas, Sean P., Garris, Christopher S., Kohler, Rainer H., Kitaoka, Maya, Cuccarese, Michael F., Yang, Katherine S., Miller, Miles A., Carlson, Jonathan C., Freeman, Gordon J., Anthony, Robert M., Weissleder, Ralph, Pittet, Mikael J.
Gepubliceerd in Sci Transl Med (2017)

SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions

door Pucci, Ferdinando, Garris, Christopher, Lai, Charles P, Newton, Andita, Pfirschke, Christina, Engblom, Camilla, Alvarez, David, Sprachman, Melissa, Evavold, Charles, Magnuson, Angela, von Andrian, Ulrich H, Glatz, Katharina, Breakefield, Xandra O, Mempel, Thorsten R., Weissleder, Ralph, Pittet, Mikael J
Gepubliceerd in Science (2016)

Defective sphingosine-1-phosphate receptor 1 (S1P(1)) phosphorylation exacerbates T(H)17-mediated autoimmune neuroinflammation

door Garris, Christopher S., Wu, Linfeng, Acharya, Swati, Arac, Ahmet, Blaho, Victoria A., Huang, Yingxiang, Moon, Byoung San, Axtell, Robert C., Ho, Peggy P., Steinberg, Gary K., Lewis, David B., Sobel, Raymond A., Han, David K., Steinman, Lawrence, Snyder, Michael P., Hla, Timothy, Han, May H.
Gepubliceerd in 2013

Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy

door Pfirschke, Christina, Engblom, Camilla, Rickelt, Steffen, Cortez-Retamozo, Virna, Garris, Christopher, Pucci, Ferdinando, Yamazaki, Takahiro, Colame, Vichnou Poirier, Newton, Andita, Redouane, Younes, Lin, Yi-Jang, Wojtkiewicz, Gregory, Iwamoto, Yoshiko, Mino-Kenudson, Mari, Huynh, Tiffany G., Hynes, Richard O., Freeman, Gordon J., Kroemer, Guido, Zitvogel, Laurence, Weissleder, Ralph, Pittet, Mikael J.
Gepubliceerd in Immunity (2016)

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

door Han, May H., Lundgren, Deborah H., Jaiswal, Siddhartha, Chao, Mark, Graham, Kareem L., Garris, Christopher S., Axtell, Robert C., Ho, Peggy P., Lock, Christopher B., Woodard, Joslyn I., Brownell, Sara E., Zoudilova, Maria, Hunt, Jack F.V., Baranzini, Sergio E., Butcher, Eugene C., Raine, Cedric S., Sobel, Raymond A., Han, David K., Weissman, Irving, Steinman, Lawrence
Gepubliceerd in 2012

Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12

door Garris, Christopher S., Arlauckas, Sean P., Kohler, Rainer H., Trefny, Marcel P., Garren, Seth, Piot, Cécile, Engblom, Camilla, Pfirschke, Christina, Siwicki, Marie, Gungabeesoon, Jeremy, Freeman, Gordon J., Warren, Sarah E., Ong, SuFey, Browning, Erica, Twitty, Christopher G., Pierce, Robert H., Le, Mai H., Algazi, Alain P., Daud, Adil I., Pai, Sara I., Zippelius, Alfred, Weissleder, Ralph, Pittet, Mikael J.
Gepubliceerd in Immunity (2018)

Tissue-specific macrophage responses to remote injury impact the outcome of subsequent local immune challenge

door Hoyer, Friedrich Felix, Naxerova, Kamila, Schloss, Maximilian J., Hulsmans, Maarten, Nair, Anil V., Dutta, Partha, Calcagno, David M., Herisson, Fanny, Anzai, Atsushi, Sun, Yuan, Wojtkiewicz, Gregory, Rohde, David, Frodermann, Vanessa, Vandoorne, Katrien, Courties, Gabriel, Iwamoto, Yoshiko, Garris, Christopher S., Williams, David L., Breton, Sylvie, Brown, Dennis, Whalen, Michael, Libby, Peter, Pittet, Mikael J., King, Kevin R., Weissleder, Ralph, Swirski, Filip K., Nahrendorf, Matthias
Gepubliceerd in Immunity (2019)

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF(high) neutrophils

door Engblom, Camilla, Pfirschke, Christina, Zilionis, Rapolas, Martins, Janaina da Silva, Bos, Stijn A., Courties, Gabriel, Rickelt, Steffen, Severe, Nicolas, Baryawno, Ninib, Faget, Julien, Savova, Virginia, Zemmour, David, Kline, Jaclyn, Siwicki, Marie, Garris, Christopher, Pucci, Ferdinando, Liao, Hsin-Wei, Lin, Yi-Jang, Newton, Andita, Yaghi, Omar K., Iwamoto, Yoshiko, Tricot, Benoit, Wojtkiewicz, Gregory R., Nahrendorf, Matthias, Cortez-Retamozo, Virna, Meylan, Etienne, Hynes, Richard O., Demay, Marie, Klein, Allon, Bredella, Miriam A., Scadden, David T., Weissleder, Ralph, Pittet, Mikael J.
Gepubliceerd in Science (2017)