Tissue-specific macrophage responses to remote injury impact the outcome of subsequent local immune challenge

Myocardial infarction, stroke and sepsis trigger systemic inflammation and organism-wide complications that are difficult to manage. Here we examined the contribution of macrophages residing in vital organs to the systemic response after these injuries. We generated a comprehensive catalog of change...

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Veröffentlicht in:Immunity
Hauptverfasser: Hoyer, Friedrich Felix, Naxerova, Kamila, Schloss, Maximilian J., Hulsmans, Maarten, Nair, Anil V., Dutta, Partha, Calcagno, David M., Herisson, Fanny, Anzai, Atsushi, Sun, Yuan, Wojtkiewicz, Gregory, Rohde, David, Frodermann, Vanessa, Vandoorne, Katrien, Courties, Gabriel, Iwamoto, Yoshiko, Garris, Christopher S., Williams, David L., Breton, Sylvie, Brown, Dennis, Whalen, Michael, Libby, Peter, Pittet, Mikael J., King, Kevin R., Weissleder, Ralph, Swirski, Filip K., Nahrendorf, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892583/
https://ncbi.nlm.nih.gov/pubmed/31732166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.10.010
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