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In vivo imaging reveals a tumor-associated macrophage mediated resistance pathway in anti-PD-1 therapy
Monoclonal antibodies targeting the immune checkpoint Programmed Death-1 (aPD-1 mAbs) have demonstrated impressive benefits for the treatment of some cancers; yet, these drugs are not always effective and we still have a limited understanding of the mechanisms that contribute to their efficacy or la...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5734617/ https://ncbi.nlm.nih.gov/pubmed/28490665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal3604 |
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