In vivo imaging reveals a tumor-associated macrophage mediated resistance pathway in anti-PD-1 therapy

Monoclonal antibodies targeting the immune checkpoint Programmed Death-1 (aPD-1 mAbs) have demonstrated impressive benefits for the treatment of some cancers; yet, these drugs are not always effective and we still have a limited understanding of the mechanisms that contribute to their efficacy or la...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Arlauckas, Sean P., Garris, Christopher S., Kohler, Rainer H., Kitaoka, Maya, Cuccarese, Michael F., Yang, Katherine S., Miller, Miles A., Carlson, Jonathan C., Freeman, Gordon J., Anthony, Robert M., Weissleder, Ralph, Pittet, Mikael J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734617/
https://ncbi.nlm.nih.gov/pubmed/28490665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal3604
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