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In vivo imaging reveals a tumor-associated macrophage mediated resistance pathway in anti-PD-1 therapy

Monoclonal antibodies targeting the immune checkpoint Programmed Death-1 (aPD-1 mAbs) have demonstrated impressive benefits for the treatment of some cancers; yet, these drugs are not always effective and we still have a limited understanding of the mechanisms that contribute to their efficacy or la...

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Detalles Bibliográficos
Publicado en:Sci Transl Med
Main Authors: Arlauckas, Sean P., Garris, Christopher S., Kohler, Rainer H., Kitaoka, Maya, Cuccarese, Michael F., Yang, Katherine S., Miller, Miles A., Carlson, Jonathan C., Freeman, Gordon J., Anthony, Robert M., Weissleder, Ralph, Pittet, Mikael J.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734617/
https://ncbi.nlm.nih.gov/pubmed/28490665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal3604
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