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In vivo imaging reveals a tumor-associated macrophage mediated resistance pathway in anti-PD-1 therapy

Monoclonal antibodies targeting the immune checkpoint Programmed Death-1 (aPD-1 mAbs) have demonstrated impressive benefits for the treatment of some cancers; yet, these drugs are not always effective and we still have a limited understanding of the mechanisms that contribute to their efficacy or la...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Transl Med
Main Authors: Arlauckas, Sean P., Garris, Christopher S., Kohler, Rainer H., Kitaoka, Maya, Cuccarese, Michael F., Yang, Katherine S., Miller, Miles A., Carlson, Jonathan C., Freeman, Gordon J., Anthony, Robert M., Weissleder, Ralph, Pittet, Mikael J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734617/
https://ncbi.nlm.nih.gov/pubmed/28490665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal3604
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